Museum of Science and Industry
The city's largest museum is spread about two huge warehouses and the world's oldest passenger railway terminal. If there's anything you want to know about the Industrial Revolution and Manchester's key role in it, you'll find it among this collection of steam engines and locomotives, factory machinery from the mills and exhibitions.
Market Restaurant
Excellent British cuisine is on the menu at this Northern Quarter restaurant - and it changes every month or so to take account of the season's best. While the decor isn't too pretty, the beer list is a cracker.
Cord Bar
The Cord bar is cool enough to have booths lined with brown corduroy and still be cool. The beer list in this snug little spot will delight the thirsty and competitive types might like to try their hands at table-soccer. Music is often provided by local DJs playing their favourite tracks; just the soundtrack for a misty Mancunian evening.
Affleck's Palace
Rag-trade wholesalers have given way to independent retailers stocking all manner of hip urban wear, retro fashions and other left-of-centre threads. At the heart of it all is Affleck's Palace, a four-storey warehouse full of outlets that Manchester's teenage Goths and the rest of the gloomerati have turned into a social day out.
Castlefield Hotel
The Castlefield has all the insipid charm of a good-quality business hotel - comfortable, well-equipped rooms, pedestrian decor and good service. But it's the reasonable rates, wonderful canalside location and the on-site fitness centre that really make it stand out from the herd.
Oklahoma Cafe
The Oklahoma is a trendy cafe, specialising in organic vegie and vegan food. Along with a quirky gift shop, this a cosy spot to spend a rainy afternoon in the Northern Quarter. The toasties and wraps are delicious, but it's the excellent organic soups that kept us coming back for more. Great fair trade coffe.
Tampopo
Fast and furiously efficient, you're in and out of this Asian fusion canteen-style restaurant before you can learn the difference between the various gorengs (noodles or rice). The food is uniformly excellent and well worth the 30-second wait. There are vegan, vego and allergy-sensitive meals available.
Club V
White leather sofas and club nights with names like Angel Deelite and Venus don't always augur well if you're looking for some really good music, but this little basement club defies all expectations with its devotion to garage and funky house.
Breakthrough Disability Service
Manchester Art Gallery
A superb collection of British art and a hefty number of European masters are on display at Manchester Art Gallery. The older wing, designed by Charles Barry (of Houses of Parliament fame) in 1834, has an impressive collection that includes 37 Turner watercolours, as well as the country's best collection of Pre-Raphaelite art. The new gallery features a permanent collection of 20th-century British art starring Lucien Freud, Francis Bacon, Stanley Spencer, Henry Moore and David Hockney.
Sankeys
Long queues and derelict surrounds make Sankeys a destination for the dedicated clubber; the venue stands in the middle of the industrial wasteland that is Ancoats. Tribal Sessions on Friday nights is regarded as a classic club night and Saturday night also sees a superb selection of techno, uplifting house and other quality electronica.
Manchester TIC
Peveril of the Peak
If you're tired of 'olde worlde' chain pubs this is the place for a quiet ale. Make sure you stop for a moment and admire its beautiful green tiled facade: it's a wonderful relic of the Georgian era, remodelled with great attention to original fittings at the turn of the century. It's named after the stagecoach that once made the regular run to London.
Love Saves the Day
The Northern Quarter's most popular café is a New York-style deli, small supermarket and sit-down eatery in one large, airy room. Everybody comes here - from crusties to corporate types - to sit around over a spot of lunch and discuss the day's goings-on. A wonderful spot.
Manchester Royal Infirmary
Earth Café
Below the Manchester Buddhist Centre, this gourmet vegetarian cafe is working hard towards becoming the first 100% organic spot in town. The food is usually excellent, always filling and ridiculously cheap.
Police Station
Ra!n
A rival to Dukes 92 for best outdoor drinking, indoors Ra!n is both trendy new-style bar and old-fashioned boozer. Whatever your mood, you'll find the right ambience in this former umbrella factory.
Chetham's Library & School of Music
Beautiful Chetham's is the city's oldest complete structure (1421). It wouldn't be half as interesting were it not for the fact that during the mid-19th century two of its regular users were Messrs Marx and Engels, whose favourite seats were by the large bay window in the main reading room.
Post Office
Harvey Nichols
The area around New Cathedral St, Exchange Sq and the impressive Triangle shopping arcade is the hot new shopping district, full of chichi boutiques and the king of all department stores, Harvey Nichols.
Urbis
The stunning glass triangle that is Urbis is a museum about how a city works and - often - doesn't work. The walls of the three floors are covered in compelling photographs, interesting statistics and informative timelines, but the best parts are the interactive videos, each of which tell stories about real people from radically different backgrounds and how they fare in Manchester.
Godlee Observatory
Maybe it's the vertiginous spiral staircase, but hardly anyone ever visits the fabulous Godlee Observatory, one of the most interesting places in town. Built In 1902, it is a fully functioning observatory with its original Grubb telescope in place; even the rope and wheels that move the telescope are original. Not only can you glimpse the heavens (if the weather allows), but the views of the city from the balcony are exceptional.
Malmaison
Drop-dead trendy and full of crushed-red velvet, deep purples, art deco ironwork and the signature black-and-white tiles, Malmaison Manchester follows the chain's quirky design style and passion for cool, though at times the whole place believes in its own hype a little too much.
Castlefield Urban Heritage Park
The Roman fort that gave birth to Manchester was built in Castlefield in AD 79. Later, this became heart of industrial Manchester, a landscape of enormous, weather-stained brick buildings and rusting cast-iron relics of canals, viaducts, bridges, warehouses and market buildings. Castlefield has now been redeveloped into an Urban Heritage Park.
Manchester Museum
A city institution for over 100 years, the Manchester Museum is an extensive and fascinating mix of natural history and social sciences. It has galleries devoted to everything from archaeology to zoology. But its drawcard is Egyptology; a number of mummies and everyday artefacts from the town sites of Kahun and Gurob were donated in 1890.
Cornerhouse Bookshop
On the ground floor of the Cornerhouse arts complex is this store specialising in contemporary visual arts and film books, specialist magazines, kitschy cards and other arty trinkets. The rest of the building contains a cafe, bar, cinema, and gallery. Connected to the gallery is a second bookshop, which sells serious books about serious art.
People's History Museum
This engrossing museum, housed in an old Edwardian pumping station, aims to deliver a fresh, comprehensive look at the social history of the working class over the past two centuries. The well laid-out exhibits include the desk at which Thomas Paine (1737-1809) wrote Rights of Man (1791) and themes such as the Peterloo Massacre and the sufragette movement.
The Ox
Please note: The Ox has just been renovated, and until one of our authors can re-review it, we would be interested to hear from any travellers who've stayed there recently...so please, post a review of your own! Meanwhile, we trust that the hotel's service continues to be of its usual high standard.